Cost conversations are essential to informed consent because patients have a right to information that they think is relevant, and patients overwhelmingly report that cost information is relevant to their medical decisions. Providers have an ethical responsibility to provide necessary information for informed consent, and therefore must discuss costs. The Shared Decision Making model is ideal for enabling this exchange of information, and decision aids are also helpful. Although barriers exist, many useful tools can help providers fulfill this obligation, and (...) encouraging progress is being made to improve cost transparency from insurers and facilities. (shrink)

Defining brain mechanisms that control and adapt motivated behavior will not only advance addiction treatment. It will help society see that addiction is a disease that erodes free will, rather than representing a free will that asks for or deserves consequences of drug-use choices. This science has important implications for understanding addiction's comorbidity in mental illness and reducing associated public health and criminal justice burdens.

Despite increasing scientific interest in self-generated thought-mental content largely independent of the immediate environment-there has yet to be any comprehensive synthesis of the subjective experience and neural correlates of affect in these forms of thinking. Here, we aim to develop an integrated affective neuroscience encompassing many forms of self-generated thought-normal and pathological, moderate and excessive, in waking and in sleep. In synthesizing existing literature on this topic, we reveal consistent findings pertaining to the prevalence, valence, and variability of emotion in (...) self-generated thought, and highlight how these factors might interact with self-generated thought to influence general well-being. We integrate these psychological findings with recent neuroimaging research, bringing attention to the neural correlates of affect in self-generated thought. We show that affect in self-generated thought is prevalent, positively biased, highly variable (both within and across individuals), and consistently recruits many brain areas implicated in emotional processing, including the orbitofrontal cortex, amygdala, insula, and medial prefrontal cortex. Many factors modulate these typical psychological and neural patterns, however; the emerging affective neuroscience of self-generated thought must endeavor to link brain function and subjective experience in both everyday self-generated thought as well as its dysfunctions in mental illness. (shrink)

In the maximal form of indirect development found in many taxa of marine invertebrates, embryonic cell lineages of fixed fate and limited division capacity give rise to the larval structures. The adult arises from set‐aside cells in the larva that are held out from the early embryonic specification processes, and that retain extensive proliferative capacity. We review the locations and fates of set‐aside cells in two protostomes, a lophophorate and a deuterostome. The distinct adult body plans of many phyla develop (...) from homologous set‐aside cells within homologous larvae. We argue that the stocks from which these phyla arose utilized these respective larvae, and the diversity of their adult body plans reflects diverse pattern formation processes executed in their set‐aside cell populations. Chordates and arthropods develop directly, but share adult characters with indirectly developing phyla. Thus the deuterostome and protostome stocks that were ancestral to chordates and arthropods, respectively, also utilized maximal indirect development. (shrink)

Núñez and colleagues (2019) question whether cognitive science still exists “as a coherent academic field with a well‐defined and cohesive interdisciplinary research program.” This worry may be premature on two grounds. First, we are not convinced that the Lakatosian criterion of coalescence around a core framework is the best standard for judging whether a field is well‐defined and productive. Second, although we acknowledge that cognitive science is not as visible as we would like, we doubt that this low profile accurately (...) reflects the state of actual research and teaching programs based on the cognitive science approach. (shrink)

Núñez and colleagues (2019) question whether cognitive science still exists “as a coherent academic field with a well‐defined and cohesive interdisciplinary research program.” This worry may be premature on two grounds. First, we are not convinced that the Lakatosian criterion of coalescence around a core framework is the best standard for judging whether a field is well‐defined and productive. Second, although we acknowledge that cognitive science is not as visible as we would like, we doubt that this low profile accurately (...) reflects the state of actual research and teaching programs based on the cognitive science approach. (shrink)

A queue‐jumping argument concludes that some course of action is impermissible by likening it to the presumptively impermissible act of jumping a queue. Arguments of this sort may be found in a disparate range of contexts and in support of policies favoured by both left and right. Examples include arguments against private education and private health care but also arguments against accommodations for learning disabilities, refugee resettlement, and birthright citizenship. We infer that, although queue‐jumping arguments are strictly analogies, they constitute (...) a sufficiently distinct class of arguments to justify their separate treatment. The paper proposes an argumentation scheme for queue‐jumping arguments and demonstrates its applicability to some existing arguments of this type. (shrink)

Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable language for describing phenotypes and their genomic and environmental contexts is perhaps the most pressing scientific bottleneck to integration across many key fields in biology, including genomics, systems biology, development, medicine, evolution, ecology, and systematics. Here we survey the current phenomics landscape, including data resources and handling, and the progress that (...) has been made to accurately capture relevant data descriptions for phenotypes. We present an example of the kind of integration across domains that computable phenotypes would enable, and we call upon the broader biology community, publishers, and relevant funding agencies to support efforts to surmount today's data barriers and facilitate analytical reproducibility. (shrink)

"The French philosopher Nicolas Malebranche popularized the doctrine of occasionalism in the late seventeenth century. Occasionalism is the thesis that God alone is the true cause of everything that happens in the world, and created substances are merely "occasional causes." This doctrine was originally developed in medieval Islamic theology, and was widely rejected in the works of Christian authors in medieval Europe. Yet despite its heterodoxy, occasionalism was revived starting in the 1660s by French and Dutch followers of the philosophy (...) of René Descartes. Since the 1970s, there has been a growing body of literature on Malebranche and occasionalism. There has also been new work on the Cartesian occasionalists before Malebranche - including Arnold Geulincx, Geraud de Cordemoy and Louis de la Forge. But to date there has not been a systematic, book-length study of the reasoning that led Cartesian thinkers to adopt occasionalism, and the relationship of their arguments to Descartes' own views. This book expands on recent scholarship, to provide the first comprehensive account of seventeenth century occasionalism. Part I contrasts occasionalism with a theory of divine providence developed by Thomas Aquinas, in response to medieval occasionalists; it shows that Descartes' philosophy is compatible with Aquinas' theory, on which God "concurs" in all the actions of created beings. Part 2 reconstructs the arguments of Cartesians - such as Cordemoy and a Forge - who used Cartesian physics to argue for occasionalism. Finally, it shows how Malebranche's case for occasionalism combines philosophical theology with Cartesian metaphysics and mechanistic science"--. (shrink)

Three claims about what makes a theory “physically complete” are (1) Shimony's assertion that a complete theory says “all there is to say” about nature; (2) EPR's requirement that a complete theory describe all “elements of reality”; and (3) Ballentine and Jarrett's claim that a “predictively complete” theory must obey a condition used in Bell deviations. After introducing “statistical completeness” as a partial formalization of (1), we explore the logical and motivational relationships connecting these completeness conditions. We find that statistical (...) completeness motivates but does not imply Jarrett's completeness condition, because Jarrett's condition encodes further intuitions about locality and causality. We also dispute Ballentine and Jarrett's claim that EPR-completeness implies Jarrett's completeness condition. (shrink)

Four experiments supported the hypothesis that ordinary people understand free will as meaning unconstrained choice, not having a soul. People consistently rated free will as being high unless reduced by internal constraints (i.e., things that impaired people’s mental abilities to make choices) or external constraints (i.e., situations that hampered people’s abilities to choose and act as they desired). Scientific paradigms that have been argued to disprove free will were seen as reducing, but usually not eliminating free will, and the reductions (...) were because of constrained conscious choice. We replicated findings that a minority of people think lacking a soul reduces free will. These reductions in perceived free will were fully explained by reductions in people’s perceived abilities to make conscious decisions. Thus, some people do think you need a soul to have free will—but it is because they think you need a soul to make conscious decisions. (shrink)

Over-time variability characterizes not only individual-level emotions, but also group-level emotions, those that occur when people identify with social groups and appraise events in terms of their implications for those groups. We discuss theory and research regarding the role of emotions in intergroup contexts, focusing on their dynamic nature. We then describe new insights into the causes and consequences of emotional dynamics that flow from conceptualizing emotions as based in group membership, and conclude with research recommendations.

In a seventeenth-century English landscape populated with towering political and philosophical figures like Hobbes, Harrington, Cromwell, Milton, and Locke, William Penn remains in many ways a man apart. Yet despite being widely neglected by scholars, he was a sophisticated political thinker who contributed mightily to the theory and practice of religious liberty in the early modern Atlantic world. In this long-awaited intellectual biography of William Penn, Andrew R. Murphy presents a nuanced portrait of this remarkable entrepreneur, philosopher, Quaker, and (...) politician.Liberty, Conscience, and Toleration focuses on the major political episodes that attracted William Penn's sustained attention as a political thinker and actor: the controversy over the Second Conventicle Act, the Popish Plot and Exclusion Crisis, the founding and settlement of Pennsylvania, and the contentious reign of James II. Through a careful examination of writings published in the midst of the religious and political conflicts of Restoration and Revolutionary England, Murphy contextualizes the development of Penn's thought in England and America, illuminating the mutual interconnections between Penn's political thought and his colonizing venture in America. An early advocate of representative institutions and religious freedom, William Penn remains a singular figure in the history of liberty of conscience. His political theorizing provides a window into the increasingly vocal, organized, and philosophically sophisticated tolerationist movement that gained strength over the second half of the seventeenth century. Not only did Penn attempt to articulate principles of religious liberty as a Quaker in England, but he actually governed an American polity and experienced firsthand the complex relationship between political theory and political practice. Murphy's insightful analysis shows Penn's ongoing significance to the broader study of Anglo-American political theory and practice, ultimately pointing scholars toward a new way of understanding the enterprise of political theory itself. (shrink)

The COVID-19 pandemic has affected the way many people live their lives. The increasing amount of time spent indoors and isolated during periods of lockdown has been accompanied by an increase in the time people spend playing video games. One such game which soared in popularity during the early stages of the pandemic was Animal Crossing: New Horizons. Through semi-structured interviews with players, and using a theory-informed qualitative analysis, we document and examine players’ motivations and experiences playing Animal Crossing: New (...) Horizons during the pandemic. Findings suggest that playing the game helped satisfy various psychological needs—autonomy, relatedness, and competence—as described by Self-Determination Theory. Conversely, players stopped playing the game when they found that their psychological needs were thwarted or better met through other activities. Our findings offer support that video games can offer psychological relief in stressful contexts by providing opportunities for people to satisfy key psychological needs. Theoretical and practical implications are discussed. (shrink)

It is widely suspected that arguments from conceivability, at least in some of their more notorious instances, are unsound. However, the reasons for the failure of conceivability arguments are less well agreed upon, and it remains unclear how to distinguish between sound and unsound instances of the form. In this paper I provide an analysis of the form of arguments from conceivability, and use this analysis to diagnose a systematic weakness in the argument form which reveals all its instances to (...) be, roughly, either uninformative or unsound. I illustrate this conclusion through a consideration of David Chalmers. (shrink)

Apropos congregatio Zetzel remarks ‘the metaphor is qualified by quasi…, as it more properly refers to animals rather than men’. It seems doubtful, however, that in general the -grego compounds were at this date felt as vividly metaphorical: segrego is used of human beings as early as Plautus and Terence ; aggrego is commonly so used by Cicero. Moreover, our passage is the first attestation of congregatio. Cicero uses the word three times in De Finibus, of which the latter two (...) passages also refer to human beings but are without quasi. Hence the use of quasi in our passage is likely to be related above all to the newness of the term, albeit the etymology may be more strongly felt in a new coinage. Cf. TLL 4, 288.26ff. (shrink)

America's supposed moral decline from an imagined golden age, and the threat of divine punishment for the sin of straying from the path of righteousness, have been consistent themes in its political and religious rhetoric. In Prodigal Nation, Andrew Murphy investigates the jeremiad's historical roots and probes the ways in which it continues to illuminate themes and tensions in American social and political life.

We have studied a number of long-term meditators in previous studies. The purpose of this study was to determine if there are differences in baseline brain function of experienced meditators compared to non-meditators. All subjects were recruited as part of an ongoing study of different meditation practices. We evaluated 12 advanced meditators and 14 non-meditators with cerebral blood flow SPECT imaging at rest. Images were analyzed with both region of interest and statistical parametric mapping. The CBF of long-term meditators was (...) significantly higher compared to non-meditators in the prefrontal cortex, parietal cortex, thalamus, putamen, caudate, and midbrain. There was also a significant difference in the thalamic laterality with long-term meditators having greater asymmetry. The observed changes associated with long-term meditation appear in structures that underlie the attention network and also those that relate to emotion and autonomic function. (shrink)

This article explores the founding of Pennsylvania as a window into the complex relationship between political theory and political practice. I argue that this founding illustrates both the importance and the limits of political theory to the study of political life. On the one hand, theorizing new societies is vitally important, because founding documents give shape to the aspirations of both founders and citizens. In this case, the founder's plans for his colony were the product of a great deal of (...) political theorizing, grounded in Penn's Quakerism and his active role in English religious and political life. But theory's importance to the study of actual foundings (and, I argue, politics more generally) is inherently limited, as well, since the colony's theoretical foundations were themselves evolving and unstable, and the translation of ideas into practice is only ever partial. After a careful consideration of the many founding documents produced by Penn between spring 1681 and summer 1682, and a close examination of developments in Pennsylvania from late 1682 through Penn's departure in summer 1684, I close by reflecting on what the case of Pennsylvania might tell us about the broader study of political theory and political practice. I suggest that we need a more flexible understanding of what political theory 'is' if we want to make sense of thinkers like Penn who theorized out of their deep involvement in the thick of actual governing. (shrink)

dixerit hoc idem Epicurus, semper beatum esse sapientem … quem quidem, cum summis doloribus conficiatur, ait dicturum: ‘quam suaue est! quam nihil curo!’ non pugnem cum homine, cur tantum †habeat† in natura boni …This text, containing Cicero's oft-repeated canard, is deeply problematic. Both Reynolds and Moreschini resort to daggers here. Madvig's abeat for habeat has failed to convince, since Cicero appears to use abeo metaphorically without specifying the place of origin or destination of movement within a narrowly circumscribed semantic field (...) which does not encompass our passage. C.F.W. Müller, on the other hand, offered aberret, which can appear without such specification in the sense ‘be deceived’ or the like. Editors evidently hesitate, however, because of the difficulty of explaining the corruption. Perhaps one might rather consider the merits of haereat. haereo can mean ‘be stuck in difficulties’, but the usage is uncommon enough that it could easily have been a stumbling block for an inattentive scribe. Moreover, in some scripts where r is written with somewhat elongated hasta and an arc curving down, it can be easily confused with b; and once haebeat appeared, the ‘correction’ to habeat was all but inevitable. (shrink)

De fato 35 is part of Cicero's argument against the Stoic theory of causation. He claims in general that the Stoic chain of causes consists of antecedent but not efficient causes. To the examples cited in the previous chapter he adds verses from the opening of Ennius’ Medea exul (lines 208–11 Jocelyn = FRL 2 and TRF 89.1–4) containing the Nurse's lamentation over the origins of the Argonautic expedition that led, ultimately, to Medea's current mental distress. Then follows the question (...) quorsum haec praeterita? and the answer quia sequitur illud, ‘nam numquam era errans mea domo ecferret pedem | Medea, animo aegro, amore saeuo saucia’, non ut eae res causam adferrent amoris, citing Ennius, Medea exul 215–16 Jocelyn = FRL 2 and TRF 89.8–9. Editors and commentators have struggled to explain the relation of the answer to the question. Here it is argued that the relation becomes clear if one adopts non for non and punctuates with a query after amoris. The sense will be: ‘Why have these past events been cited? In view of the sequel … was it not so that they bring on the cause of love?’ In other words, the Nurse, like the Stoics in Cicero's view, cites antecedent events as if they were efficient causes. (shrink)

quod idem [sc. the invalidity of Clodius’ legislation] tu, Lentule, uidisti in ea lege quam de me tulisti. nam non est ita latum ut mihi Romam uenire liceret, sed ut uenirem; non enim uoluisti id quod licebat ferre ut liceret, sed me ita esse in re publica magis ut arcessitus imperio populi Romani uiderer quam administrandam ciuitatem restitutus.

Book 1 of De Natura Deorum exhibits in a nutshell Cicero's philosophical method, with the prior part stating the case for Epicurean theology, the latter part refuting it. Thus the reader observes Cicero at work in both constructive and skeptical modes as well as his art of characterizing speakers. Prefaced to the Book is Cicero's most elaborate justification of his philosophical writing. The Book thus makes an ideal starting point for the study of Cicero's philosophica or indeed of any philosophical (...) writing in Latin, since it delineates the problems such a project raised in the minds of Roman readers and shows how Cicero thought they could be met. There is also a systematic and detailed doxography of ancient views about the deity, an important document in itself, presented from an Epicurean perspective. The volume's Introduction situates this text within Cicero's intellectual development and ancient reflection about the gods. (shrink)